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However, patient experience is mixed: while some members report no difference between the two methods, others find they do not achieve the same symptom resolution with SC injections

We understand that a variety of factors can affect the duration of the Vitamin B12 shots efficacy

From our collective experience and reviewing extensive literature, starting doses for subcutaneous or intramuscular injections often fall within the range of 0.5mg to 2mg per day for a standard research model (e.g., a 70kg equivalent)

Yet this advice is not widely acted upon by GPs

This condition is characterized by a lack of intrinsic factor, a protein that plays a crucial role in helping the body absorb vitamin B12 (Ankar, 2020)